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What is an alternative to Zantac? But another alternative is to switch to less powerful and less expensive over-the-counter acid blockers like Zantac or Tagamet, or even old-fashioned antacids like Rolaids and Pepto-Bismol, which doctors say offer relief to many people with mild to moderate heartburn. How do doctors test for GERD? To confirm a diagnosis of GERD, or to check for complications, your doctor might recommend: Upper endoscopy. Ambulatory acid (pH) probe test. Esophageal manometry. X-ray of your upper digestive system.
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