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Can taking estrogen cause cancer? Estrogen -only HRT increases the risk of breast cancer, but only when used for more than 10 years. Estrogen -only HRT also can increase the risk of ovarian cancer. The higher breast cancer risk from using HRT is the same for so-called "bioidentical" and "natural" hormones as it is for synthetic hormones.
Is high estradiol dangerous? High levels of estrogen can put you at a higher risk of some other conditions. For example, elevated estrogen levels are a risk factor for breast cancer and ovarian cancer. According to the American Cancer Society (ACS), estrogen dominance can also increase your risk of endometrial cancer.
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