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Is Abilify a mood stabilizer or antipsychotic? Aripiprazole can be effective in treating the acute manic episodes of bipolar disorder in adults, adolescents and children. However, its effect is only useful for the manic phases with little or no effect on the depressive phases. For this reason, aripiprazole is often used in conjunction with mood stabilizers.
Why are antipsychotics sedating? Efficacy and sedation Antipsychotics are thought to exert their effect by antagonism of postsynaptic dopamine D2 and serotonin 5HT2A receptors and possibly other receptors in the brain. Four SGAs—risperidone, olanzapine, quetiapine, and ziprasidone—act as dopamine D2 and 5HT2A antagonists.
How long does it take for Abilify to get out of your system? The mean elimination half-lives are about 75 hours and 94 hours for aripiprazole and dehydro- aripiprazole, respectively.
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